1. First Hokage: The "God of Shinobi" faced an assassination attempt by Kakuzu but remained unharmed.
2. Fourth Mizukage: Yagura, a perfect jinchuriki, evaded multiple assassination attempts by Zabuza Momochi and caused his betrayal.
3. Third Kazekage: Assassinated by Sasori, the "Strongest Kazekage" became a puppet, ending his powerful reign.
4. Fourth Kazekage: Orochimaru's assassins killed the magnetic sand manipulator and covered his body in insects.
5. Fifth Kazekage: Gaara, the Fifth Kazekage, defended himself against his father's assassination attempt and triggered his tailed beast transformation.